Spray a slow cooker with nonstick cooking spray and place the chicken breasts into the slow cooker.

In a small dish combine the salt, ground black pepper, paprika, onion powder, and garlic powder. Mix well.

Sprinkle half of the seasoning mix over the chicken breasts. Use a pair of tongs to flip the chicken and sprinkle the remaining seasoning on the other side.

Pour the cream of chicken soup, diced tomatoes, and Ro-Tel over the chicken. Place a lid on the slow cooker, and cook for 4 hours on high.

Remove the lid and shred the cooked chicken with two forks. Add the cayenne pepper, smoked paprika, shredded cheese, and sour cream. Mix well.

While the cheese melts, prepare the spaghetti according to the package instructions. Drain.

Place the spaghetti into the crockpot and serve immediately.